Aerius syrup is effective in children with Allergic Rhinitis.¹
 

Desloratadine exposure in children appears to be similar to that observed in adults, in whom efficacy has been established.²





1. Rossi GA, Tosca MA, Passalacqua G, Bianchi B, Le Grazie C, Canonica GW. Evidence of desloratadine syrup efficacy and tolerability in children with pollen-induced allergic rhinitis. Allergy. 2005;60(3):4167.
2. Gupta S, Khalilieh S, Kantesaria B, Banield C. Pharmacokinetics of desloratadine in children between 2 and 11 years of age. British Journal of Clinical Pharmacology. 2007;63(5):53440..

In children with co-existing asthma and/or conjunctivitis, induced:¹



 

1. Rossi GA, Tosca MA, Passalacqua G, Bianchi B, Le Grazie C, Canonica GW. Evidence of desloratadine syrup eicacy and tolerability in children with pollen-induced allergic rhinitis. Allergy. 2005;60(3):4167.

No severe or serious adverse events occurred and no clinically relevant changes were noted in median clinical laboratory test values or mean vital signs.¹

1. Bloom M, Staudinger H, Herron J. Safety of desloratadine syrup in children. Current Medical Research and Opinion. 2004;20(12):195965.

Aerius is taken with or without food.^1,2

- Unlike fexofenadine, the bioavailability of Aerius is not influenced by grapefruit juice.

- The rate and extent of absorption of fexofenadine were reduced by 30% by the consumption of grapefruit juice.³

- Grapefruit juice has no effect on the disposition of desloratadine.^1-3

Dosage:⁴

Children aged 1 to 5 years: 2.5 ml once daily.

Children aged 6 to 11 years: 5 ml once daily.

1. Aerius^TM Tablet PIL.
2. Aerius^TM Syrup PIL.
3. Banfield C, Gupta S, Marino M, Lim J, Arime M. Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine. Clinical Pharmacokinetics. 2002;41(4):3118.
4. Bloom M, Staudinger H, Herron J. Safety of desloratadine syrup in children. Current Medical Research and Opinion. 2004;20(12):1959-65.