Bepanthen® Derma

for Dry Skin Prevention and Daily Skin Care Routine delivers immediate and long-lasting hydration.

  • •
    Features a unique formula — endorsed by experts.1
  • •
    Tackles dry skin on many levels, from the inside out.1
    • •
      Addresses the underlying cause.1
    • •
      Provides immediate and lasting hydration.*
  • •
    Supports a balanced healthy microbiome, known to help keep the skin hydrated.
  • •
    From a brand with over 75 years experience in skin healing.
  • •
    Free from preservatives, fragrance and colorants.

Bepanthen® Derma

addresses the underlying cause for dry skin re-occurrence (disturbed epidermal differentiation) which will support in dry skin prevention and daily skin care.

The science behind the Bepanthen® Derma

Unique formula icon

Unique formula that tackles dry skin on many levels.1

Hydration icon

Delivers immediate and lasting hydration.*

Skin structure illustration
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Contains five key ingredients, endorsed by a global expert panel.1

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Takes an ‘inside-out approach’ to restore healthy skin.2-4

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Works in harmony with the skin’s natural microbiome, ensuring its balance is not disturbed.

Bepanthen® Derma

contains five key ingredients to effectively tackle dry skin from the inside out

*Claim relates to body lotions and face creams only.

References:
1. Proksch E, et al. Dry skin management: practical approach in light of latest research on skin structure and function. J Dermatolog Treat 2020;31:716-722. 2. Proksch E. The role of emollients in the management of diseases with chronic dry skin. Skin Pharmacol Physiol. 2008;21(2):75–80. 3. Gehring W, et al. Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration: results of a human in vivo study. Arzneimitte of orschung 2000;50:659–663. 4. Proksch E and Lachapelle JM. The management of dry skin with topical emollients – recent perspectives. JDDG 2005;3:768–74. 5. Gehring W. Nicotinic acid/niacinamide and the skin. J Cosmet Dermatol 2004;3(2):88–93. 6. Wohlrab J and Kreft D. Niacinamide -mechanisms of action and its topical usein dermatology. Skin Pharmacol Physiol 2014;27:311–315.

A Global Expert Panel Review recommends five key components to effectively tackle dry skin

A group of specialists met in 2017 to discuss the latest research into the pathophysiology of dry skin at the molecular level.1

They concluded that:

An ideal emollient needs five key components:

  • • Antipruritics/soothing agent.
  • • Humectants.
  • • Non-physiological lipids.
  • • Physiological lipids.
  • • Agents that support epidermal differentiation.
Erhardt Proksch
Erhardt Proksch
Department of Dermatology
University of Kiel, Germany
Enzo Berardesca
Enzo Berardesca
San Gallicano Dermatological Institute
Rome, Italy
Johan Englom
Johan Englom
Department of Biomedical Science, Faculty of Health and Society
Malmö University, Malmö, Sweden
Laurent Misery
Laurent Misery
Department of Dermatology, University Hospital of Brest
Laboratory of Neurosciences, University of Western Brittany, Brest, France
Joke Bouwstra
Joke Bouwstra
Division of Drug Delivery Technology, Leiden Academy Centre for Drug Research
Leiden, The Netherlands

Reference:
1. Proksch E, et al. Dry skin management: practical approach in light of latest research on skin structure and function. J Dermatolog Treat 2020;31:716-722.

Bepanthen® Derma takes an inside-out approach to support normal epidermal differentiation and restore healthy skin1-3

Reference:
1. Proksch E. The role of emollients in the management of diseases with chronic dry skin. Skin Pharmacol Physiol. 2008;21(2):75–80. 2. Gehring W, et al. Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration: results of a human In-vivo study. Arzneimitteoforschung 2000;50:659–663. 3. Proksch E and Lachapelle JM. The management of dry skin with topical emollients – recent perspectives. JDDG 2005;3:768–774.

Bepanthen® Derma moisturises your skin immediately and supports your skin microbiome
1

Keeps the skin moisturized and reduces the space for growth of bad bacteria, as they prefer to grow on dry skin flakes.

2

Supports the skins microbiome by helping good bacteria to boost (natural) water magnets, leaving the skin more moisturized for longer.

3

Supports the skin’s biological activity and preserves microbiome diversity, known to be beneficial for healthy skin.

4

Works in harmony with the skin’s natural microbiome, ensuring its balance is not disturbed.

Restoring Body Lotion
Restoring Body Lotion

Specially formulated for dry skin1

DRY SKIN AND THE SUN

Exposure to ultraviolet (UV) radiation from the sun is damaging and can lead to dry skin by:2,3

  • • Compromising the skin barrier function.
  • • Increasing transepidermal water loss (TEWL).

In Saudi Arabia, the UV index is elevated throughout the year4, warranting careful exposure.3,5

Replenishing Body Lotion
Restoring Body Lotion

Specially Formulated For Very Dry And Sensitive Skin.6

DRY SKIN AND AGE

  • • Elderly skin is associated with reduced skin barrier function and slower repair following damage.7,8
  • • Reduced lipid synthesis9 and other epidermal alterations lead to dry skin and pruritus, which have a substantial negative effect on quality of life.10, 11
Gentle Body Cleanser
Gentle Body Cleanser

Dry & Sensitive Skin

  • • Soap-free, gentle body wash.
  • • Specially formulated for dry skin.
  • • Preservative free.
  • • Clinically proven.
table

References:
1.Bayer. Cosmetic Test Report IMPACT 20712(In-Home Use Test). R. Olsavszky: Human In Use Test under Dermatological Control and Instrumental Evaluation UI1614317. 2.Proksch E and Lachapelle JM. The management of dry skin with topical emollients – recent perspectives. JDDG 2005;3:768–774. 3.Biniek K. Solar UV radiation reduces the barrierfunction ofhuman skin. PNAS 2012;109:17111–17116. 4.Average UV index Riyadh, Saudi Arabia. Available from: https://www.weather atlas.com/ en/saudiarabia/ riyadh climate#uv_index. 5.World Health Organization. Global Solar UV Index: A Practical Guide. World Health Organization: Geneva, Switzerland, 2002. 6.Bayer. Cosmetic Test Report IMPACT 20711 (In- Home Use Test). R. Olsavszky: Human In Use Test under Dermatological Control and Instrumental Evaluation. UI1614318. 7.Blume-Peytavi U, et al. Age-associated skin conditions and diseases: Current perspectives and future options. Gerontologist 2016;56:S230–S242. 8.Choi EH, et al. Stratum corneum acidification is impaired in moderately aged human and murineskin. J Invest Dermatol 2007;127:2847–2856. 9.Jensen JM, et al. Acid and neutral sphingomyelinase, ceramide synthase, and acid ceramidase activities in cutaneous aging. Exp Dermatol 2005;14:609–618. 10.Chang AL, et al. Geriatric dermatology review: Major changes in skin function in older patients and their contribution to common clinical challenges. J Am Med Dir Assoc 2013;14:724–730. 11.Garibyan L, et al. Advanced aging skin and itch: Addressing an unmet need. Dermatol Ther 2013;26:92–103. 12.Proksch E, et al. Dry skin management: practical approach in light of latest research on skin and structure and function. J Dermatological Treatment 2019;19:1–7. 13.Proksch E. The role of emollients in the management of diseases with chronic dry skin. Skin Pharmacol Physiol 2008;21(2):75-80. 14.Gehring W. Nicotinic acid/niacinamide and the skin. J Cosmet Dermatol 2004;3(2):88–93. 15.Wohlrab J and Kreft D. Niacinamide - mechanisms of action and its topical use in dermatology. Skin Pharmacol Physiol 2014;27:311–315.

Regenerating
Night Face Cream
Regenerating Night Face Cream

Specially formulated for “very dry and rough skin”

  • • Exposure to a dry environment, makes the skin more susceptible to mechanical stress, with transepidermal water loss correlated with relative humidity and skin temperature, respectively.1
Restoring Daily
Face Cream
Restoring Daily Face Cream with SPF25

Restoring Daily Face Cream with SPF252

  • • Contains dexpanthenol repair complex to soothe and repair dry skin, and with SPF25 has the extra benefit that it will protect her skin from UV damage.
Bepanthen® Derma Gentle Cleansing Face Wash
Face
Cleanser
Face Cleanser
Gentle Face Cleanser Daily Wash Gel.

DRY AND Sensitive skin

    • • Soap-free, gentle body wash.
    • • Specially formulated for dry skin.
    • • Preservative free.
    • • Clinically proven.
Proven across three levels of scientific evidence2, 3
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Relieving and moisturizing – delivers immediate and long-lasting hydration.

Hydration icon

Repairing the lipid matrix – increased lipid level.

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Restoring the skin barrier – reduction of TEWL in damaged skin – supports skin repair.

SPF: sun protection factor; UV: ultraviolet; TEWL: trans-epidermal water loss.

References:
1. Jung M, et al. Exposure to cold airflow alters skin pH and epidermal filaggrin degradation products in children with atopic dermatitis. Allergology International. 2020;69:429–436. 2. Bayer. Cosmetic Test Report IMPACT 20716 (In-Home Use Test). S. Rharbaoui, D.K. Fook Chong: Evaluation of the Efficacy of One Facial Cosmetic Product on Hydration and Skin Lipids. UI1614323. 3. Bayer. Cosmetic Test Report IMPACT 21047 (In-Home Use Test). S. Rharbaoui, D.K. Fook Chong: Evaluation of the Efficacy of One Facial Cosmetic Product on Hydration and Skin Lipids. UI1614324.