Dry skin management typically involves application of an emollient. An ideal emollient contains five key components: humectants, non-physiological lipids, physiological lipids antipruritic/soothing agents, and agents that support epidermal differentiation…

Approximately 70 years ago, the first topical dexpanthenol-containing formulation (BepanthenTM Ointment) has been developed.…

Topical dexpanthenol acts like a moisturizer, improving stratum corneum hydration, reducing transepidermal water loss and maintaining skin softness and elasticity. Activation of fibroblast proliferation, which is of relevance in wound healing….

For adults with AD, we recommend the use of moisturizers. The use of a particular moisturizer or active ingredient in an emollient cannot be recommended based on the limited available evidence. Strength: strong , level of evidence: moderate.

Most moisturisers showed beneficial effects, producing better results when used with active treatment, prolonging time to flare, and reducing the number of flares and amount of topical corticosteroids needed to achieve similar reductions in eczema severity….

The ETFAD recommends the daily use of liberal amounts of emollients, at least 30 g/day or 1 kg/month for an adult, which should preferentially be applied in a ‘soak-and-seal’ technique…