Efficacy
Dosing
Summary
Claritine pack
Efficacy

Clarinase Repetabs…
The power of antihistamine
and decongestant in one 1,2

1. Clarinase™ Package Lealet. 2. Clarinase™ SmPC. Available at: https://www.ema.europa.eu/en/documents/referral/loratadine-pseudoephedrine-article-31-referral-annex-i-ii-iii_en.pdf. 3. Georgitis JW, Meltzer EO, Kaliner M, Weiler J, Berkowitz R. Onset-of-action for antihistamine and decongestant combinations during an outdoor challenge. Annals of Allergy, Asthma & Immunology. 2000;84(4):4519. 4. Supiyaphun P, Chochaipanichnon L, Kerekhanjanarong V, Saengpanich S. A comparative study of the side effects between pseudoephedrine in Loratadine plus Pseudoephedrine Sulfate Repetabs Tables and loratadine + pseudoephedrine tablet in treatment of allergic rhinitis in Thai patients. Journal of the Medical Association of Thailand. 2002;85(6):7227.

Clarinase™ Repetabs provide rapid and sustained relief from nasal congestion.2,3

Repetabs rapid & sustained relief process diagram
30 minutes onset graphic

Clarinase™ Repetabs are combination antihistamine and decongestant in one1

Clarinase Repetabs relieve SAR symptoms such as, sneezing, runny or itchy nose, and eyes when accompanied by nasal congestion in adults and children 12 years of age and over.1

SAR=seasonal allergic rhinitis
1. Clarinase™ Package Lealet. 2. Clarinase™ SmPC. Available at: https://www.ema.europa.eu/en/documents/referral/loratadine-pseudoephedrine-article-31-referral-annex-i-ii-iii_en.pdf.

Significant PNIF increase with Clarinase by the first hour.1

Treatment phase baseline PNIF is from the highest of three measured values prior to study treatment.1

PNIF: Peak nasal inspiratory flow. 1. Ng CC, Romaikin D, Steacy LM, et al. Comparative nasal airflow with loratadine-pseudoephedrine and Fluticasone nasal spray for allergic rhinitis. Annals of Allergy, Asthma & Immunology. 2021;127:342348.
Average percent change in PNIF over 60 minutes: Clarinase vs Placebo

Clarinase Repetabs provide at least twofold improvement
in nasal airflow than fluticasone1

PNIF: Peak nasal inspiratory flow.
1. Ng CC, Romaikin D, Steacy LM, et al. Comparative nasal airflow with loratadine-pseudoephedrine and Fluticasone nasal spray for allergic rhinitis. Annals of Allergy, Asthma & Immunology. 2021;127:342348.

Treatment phase baseline PNIF is from the highest of three measured values prior to study treatment.1

Average percent change in PNIF: Clarinase Repetabs vs Fluticasone over time

Clarinase Repetabs have superior efficacy throughout the study period vs fluticasone propionate or placebo1

PNIF: Peak nasal inspiratory flow.
1. Ng CC, Romaikin D, Steacy LM, et al. Comparative nasal airflow with loratadine-pseudoephedrine and fluticasone nasal spray for allergic rhinitis. Annals of Allergy, Asthma & Immunology. 2021;127:342348.

Treatment phase baseline PNIF is from the highest of three measured values prior to study treatment.1

Average percent change in PNIF over time: Clarinase Repetabs vs Fluticasone vs Placebo

Clarinase Repetabs are effective in symptomatic management of common cold1

The use of Repetabs in relieving common cold symptoms should produce the beneficial lessening of symptoms without production of medication-induced drowsiness, thereby enabling patients to continue their normal daily routine.

1. Berkowitz RB, Connell JT, Dietz AJ, Greenstein SM, Tinkelman DG. The effectiveness of the nonsedating antihistamine loratadine plus pseudoephedrine in the symptomatic management of the common cold. Annals of Allergy. 1989;63(4):3369..

Treatment phase baseline PNIF is from the highest of three measured values prior to study treatment.1

Total symptom score over 5 days: Clarinase vs Placebo
Dosing

TWICE

Daily

twice-daily-2x

One

Tablet

Recommended for adults
and Adolescents 12 years of age and over

1. Claritine™ Tablet Package Leaflet.
Summary
clarinase (loratadine 10 mg) had no significant effect on any of the measured variables.
  • Clarinase Repetabs are combination of antihistamine and decongestant.1,2
  • Clarinase Repetabs provide rapid and sustained relief from nasal congestion.2,3
  • Clarinase Repetabs relieve SAR symptoms when accompanied by nasal congestion.1
  • Clarinase Repetabs onset of action occurs within 30 minutes.2
  • The use of Clarinase Repetabs in relieving common cold symptoms should produce the beneficial lessening of symptoms without production of medication-induced drowsiness.4
SAR: seasonal allergic rhinitis.
1. Clarinase™ Package Leaflet. 2. Clarinase™ SmPC. Available at: https://www.ema.europa.eu/en/documents/referral/
loratadine-pseudoephedrine-article-31-referral-annex-i-ii-iii_en.pdf. 3. Georgitis JW, Meltzer EO, Kaliner M, Weiler J, Berkowitz R. Onset-of-action for antihistamine and decongestant combinations during an outdoor challenge. Annals of Allergy, Asthma & Immunology. 2000;84(4):4519. 4. Berkowitz RB, Connell JT, Dietz AJ, Greenstein SM, Tinkelman DG. The effectiveness of the nonsedating antihistamine loratadine plus pseudoephedrine in the symptomatic management of the common cold. Annals of Allergy. 1989;63(4):3369.