The history of the discovery of aspirin dates to more than 3500 years, when the bark of the willow tree was used as a natural remedy to treat pain and fever.¹

In 1897, acetylsalicylic acid was first synthesized as a chemically pure and stable compound in a Bayer laboratory in Wuppertal, Germany.¹

Two years later, Bayer launched acetylsalicylic acid in powder form on the market under the trademark name “Aspirin”.¹

About one billion people worldwide take regular aspirin.²

≈40,000 tons of aspirin are produced every year worldwide.³

In USA, >50 million people take 10 to 20 billion aspirin tablets regularly for the prevention of CVD.³

20,000 references between 2013 and 2023, for PubMed search using the keyword “aspirin”, this reflect the great interest in the pharmacological and therapeutic potential of aspirin.¹

The antiplatelet effect of aspirin led to its use in the field of cardiology, where it remains the CORNERSTONE of ANTIPLATELET therapy in patients with cardiovascular disease, in both the acute setting as well as for the long-term prevention of cardiovascular events.¹