CAC: coronary artery calcium; CVD: cardiovascular disease; CIMT: carotid intima-media thickness; CAD: coronary artery disease; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; MACE: Major adverse cardiovascular events; TIA: Transient ischemic attack; VBI: vertebrobasilar insufficiency; ACS: acute coronary syndrome; PCI: percutaneous coronary intervention; DAPT: dual antiplatelet therapy; P2Y12: Platelet adenosine diphosphate.
c Clopidogrel is recommended for 12 months DAPT if prasugrel and ticagrelor are not available, cannot be tolerated, or are contraindicated, and may be considered in older ACS patients.

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